An Improved Function to Perform Regression on Single Cell Data. — bb_monocle_regression

This function replaces bb_monocle_regression. It returns log2FoldChange instead of estimates. The log2FoldChange value is the normalized_effect value returned from the monocle regression functions.

Usage

bb_monocle_regression_better(
  cds,
  gene_or_genes,
  stratification_variable = NULL,
  stratification_value = NULL,
  form,
  linking_function = "negbinomial"
)

Arguments

cds: A cell data set object.
gene_or_genes: Genes to regress by.
stratification_variable: Optional colData column to subset the cds by internal to the function.
stratification_value: Optional value to stratify by.
form: The regression formula in the form of "~var1+var2+..."
linking_function: For the generalized linear model.

Value

A tibble containing the regression results.